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Identification of oleic acid as an endogenous ligand of GPR3 Corrections - Cell Research

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Identification of oleic acid as an endogenous ligand of GPR3 Corrections - Cell Research

Although GPR3 plays pivotal roles in both the nervous system and metabolic processes, such as cold-induced thermogenesis, its endogenous ligand remains elusive. Here, by combining structural approach (including cryo-electron microscopy), mass spectrometry analysis, and functional studies, we identify oleic acid (OA) as an endogenous ligand of GPR3.

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Identification of oleic acid as an endogenous ligand of GPR3 Corrections - Cell Research

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Identification of oleic acid as an endogenous ligand of GPR3 Corrections - Cell Research

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