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A genome-wide association study reveals the relationship between human genetic variation and the nasal microbiome - Communications Biology

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A genome-wide association study reveals the relationship between human genetic variation and the nasal microbiome - Communications Biology

The nasal cavity harbors diverse microbiota that contributes to human health and respiratory diseases. However, whether and to what extent the host genome shapes the nasal microbiome remains largely unknown. Here, by dissecting the human genome and nasal metagenome data from 1401 healthy individuals, we demonstrated that the top three host genetic principal components strongly correlated with the nasal microbiota diversity and composition.

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A genome-wide association study reveals the relationship between human genetic variation and the nasal microbiome - Communications Biology

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A genome-wide association study reveals the relationship between human genetic variation and the nasal microbiome - Communications Biology

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