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Increase in peg-asparaginase clearance as a predictor for inactivation in patients with acute lymphoblastic leukemia - Leukemia

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Increase in peg-asparaginase clearance as a predictor for inactivation in patients with acute lymphoblastic leukemia - Leukemia

Asparaginase is an essential component of acute lymphoblastic leukemia (ALL) therapy, yet its associated toxicities often lead to treatment discontinuation, increasing the risk of relapse. Hypersensitivity reactions include clinical allergies, silent inactivation, or allergy-like responses. We hypothesized that even moderate increases in asparaginase clearance are related to later inactivation.

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Increase in peg-asparaginase clearance as a predictor for inactivation in patients with acute lymphoblastic leukemia - Leukemia

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Increase in peg-asparaginase clearance as a predictor for inactivation in patients with acute lymphoblastic leukemia - Leukemia

Rate This Post

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Unlocking the Power of Knowledge for Humanity's Progress

Unlocking the Power of Knowledge
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Unlocking the Power of Knowledge
for Humanity's Progress