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Clarity on the blazing trail: clearing the way for amyloid-removing therapies for Alzheimer's disease - Molecular Psychiatry

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Clarity on the blazing trail: clearing the way for amyloid-removing therapies for Alzheimer's disease - Molecular Psychiatry

Alzheimer's disease (AD) is a progressive neurodegenerative disorder with a complex pathogenesis. Senile plaques composed of the amyloid-β (Aβ) peptide in the brain are the core hallmarks of AD and a promising target for the development of disease-modifying therapies. However, over the past 20 years, the failures of clinical trials directed at Aβ clearance have fueled a debate as to whether Aβ is the principal pathogenic factor in AD and a valid therapeutic target.

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Clarity on the blazing trail: clearing the way for amyloid-removing therapies for Alzheimer's disease - Molecular Psychiatry

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Clarity on the blazing trail: clearing the way for amyloid-removing therapies for Alzheimer's disease - Molecular Psychiatry

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