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Measuring criticality in control of complex biological networks - npj Systems Biology and Applications

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Measuring criticality in control of complex biological networks - npj Systems Biology and Applications

Recent controllability analyses have demonstrated that driver nodes tend to be associated to genes related to important biological functions as well as human diseases. While researchers have focused on identifying critical nodes, intermittent nodes have received much less attention. Here, we propose a new efficient algorithm based on the Hamming distance for computing the importance of intermittent nodes using a Minimum Dominating Set (MDS)-based control model.

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Measuring criticality in control of complex biological networks - npj Systems Biology and Applications

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