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EZH2 inhibitors promote β-like cell regeneration in young and adult type 1 diabetes donors - Signal Transduction and Targeted Therapy

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EZH2 inhibitors promote β-like cell regeneration in young and adult type 1 diabetes donors - Signal Transduction and Targeted Therapy

β-cells are a type of endocrine cell found in pancreatic islets that synthesize, store and release insulin. In type 1 diabetes (T1D), T-cells of the immune system selectively destroy the insulin-producing β-cells. Destruction of these cells leads to a lifelong dependence on exogenous insulin administration for survival. Consequently, there is an urgent need to identify novel therapies that stimulate β-cell growth and induce β-cell function.

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EZH2 inhibitors promote β-like cell regeneration in young and adult type 1 diabetes donors - Signal Transduction and Targeted Therapy

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EZH2 inhibitors promote β-like cell regeneration in young and adult type 1 diabetes donors - Signal Transduction and Targeted Therapy

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