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TXNRD1 drives the innate immune response in senescent cells with implications for age-associated inflammation - Nature Aging

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TXNRD1 drives the innate immune response in senescent cells with implications for age-associated inflammation - Nature Aging

Sterile inflammation, also known as 'inflammaging', is a hallmark of tissue aging. Cellular senescence contributes to tissue aging, in part, through the secretion of proinflammatory factors collectively known as the senescence-associated secretory phenotype (SASP). The genetic variability of thioredoxin reductase 1 (TXNRD1) is associated with aging and age-associated phenotypes such as late-life survival, activity of daily living and physical performance in old age.

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TXNRD1 drives the innate immune response in senescent cells with implications for age-associated inflammation - Nature Aging

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TXNRD1 drives the innate immune response in senescent cells with implications for age-associated inflammation - Nature Aging

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