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Multivariate genome-wide analysis of aging-related traits identifies novel loci and new drug targets for healthy aging - Nature Aging

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Multivariate genome-wide analysis of aging-related traits identifies novel loci and new drug targets for healthy aging - Nature Aging

The concept of aging is complex, including many related phenotypes such as healthspan, lifespan, extreme longevity, frailty and epigenetic aging, suggesting shared biological underpinnings; however, aging-related endpoints have been primarily assessed individually. Using data from these traits and multivariate genome-wide association study methods, we modeled their underlying genetic factor ('mvAge').

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Multivariate genome-wide analysis of aging-related traits identifies novel loci and new drug targets for healthy aging - Nature Aging

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Multivariate genome-wide analysis of aging-related traits identifies novel loci and new drug targets for healthy aging - Nature Aging

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