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Immune checkpoints in cardiac physiology and pathology: therapeutic targets for heart failure - Nature Reviews Cardiology

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Immune checkpoints in cardiac physiology and pathology: therapeutic targets for heart failure - Nature Reviews Cardiology

Immune checkpoint molecules are physiological regulators of the adaptive immune response. Immune checkpoint inhibitors (ICIs), such as monoclonal antibodies targeting programmed cell death protein 1 or cytotoxic T lymphocyte-associated protein 4, have revolutionized cancer treatment and their clinical use is increasing. However, ICIs can cause various immune-related adverse events, including acute and chronic cardiotoxicity.

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Immune checkpoints in cardiac physiology and pathology: therapeutic targets for heart failure - Nature Reviews Cardiology

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Immune checkpoints in cardiac physiology and pathology: therapeutic targets for heart failure - Nature Reviews Cardiology

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