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Oligodendroglial metabolic support of myelinated axons driven by K+ dynamics - Nature Neuroscience

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Oligodendroglial metabolic support of myelinated axons driven by K+ dynamics - Nature Neuroscience

This research elucidates that oligodendrocytes detect and respond to fast axonal spiking through K+ signaling, and that Kir4.1 channel activation has a pivotal role. This activity-driven interaction regulates axonal metabolic support by oligodendrocytes and influences lactate delivery and glucose metabolism in axons, which is essential for sustaining axonal health.

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Oligodendroglial metabolic support of myelinated axons driven by K+ dynamics - Nature Neuroscience

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Oligodendroglial metabolic support of myelinated axons driven by K+ dynamics - Nature Neuroscience

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