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Oligodendrocyte–axon metabolic coupling is mediated by extracellular K+ and maintains axonal health - Nature Neuroscience

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Oligodendrocyte–axon metabolic coupling is mediated by extracellular K+ and maintains axonal health - Nature Neuroscience

The integrity of myelinated axons relies on homeostatic support from oligodendrocytes (OLs). To determine how OLs detect axonal spiking and how rapid axon–OL metabolic coupling is regulated in the white matter, we studied activity-dependent calcium (Ca2+) and metabolite fluxes in the mouse optic nerve.

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Oligodendrocyte–axon metabolic coupling is mediated by extracellular K+ and maintains axonal health - Nature Neuroscience

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Oligodendrocyte–axon metabolic coupling is mediated by extracellular K+ and maintains axonal health - Nature Neuroscience

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