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3 months ago

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Strategies to reduce the risks of mRNA drug and vaccine toxicity - Nature Reviews Drug Discovery

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Strategies to reduce the risks of mRNA drug and vaccine toxicity - Nature Reviews Drug Discovery

mRNA formulated with lipid nanoparticles is a transformative technology that has enabled the rapid development and administration of billions of coronavirus disease 2019 (COVID-19) vaccine doses worldwide. However, avoiding unacceptable toxicity with mRNA drugs and vaccines presents challenges. Lipid nanoparticle structural components, production methods, route of administration and proteins produced from complexed mRNAs all present toxicity concerns.

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Strategies to reduce the risks of mRNA drug and vaccine toxicity - Nature Reviews Drug Discovery

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Strategies to reduce the risks of mRNA drug and vaccine toxicity - Nature Reviews Drug Discovery

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