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Controlled adsorption of multiple bioactive proteins enables targeted mast cell nanotherapy - Nature Nanotechnology

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Controlled adsorption of multiple bioactive proteins enables targeted mast cell nanotherapy - Nature Nanotechnology

Protein adsorption onto nanomaterials often results in denaturation and loss of bioactivity. Controlling the adsorption process to maintain the protein structure and function has potential for a range of applications. Here we report that self-assembled poly(propylene sulfone) (PPSU) nanoparticles support the controlled formation of multicomponent enzyme and antibody coatings and maintain their bioactivity.

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Controlled adsorption of multiple bioactive proteins enables targeted mast cell nanotherapy - Nature Nanotechnology

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Controlled adsorption of multiple bioactive proteins enables targeted mast cell nanotherapy - Nature Nanotechnology

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