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The buck stops with spermidine - Nature Chemical Biology

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The buck stops with spermidine - Nature Chemical Biology

Sirtuins remove post-translationally added acyl groups from protein lysines. New work shows the surprising metabolic fate of acyl groups removed from mitochondrial proteins—they react nonenzymatically with essential polyamine spermidine, forming previously unknown monoacylated N-glutarylspermidines and diacylated N-glutaryl,N-acetylspermidines.

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The buck stops with spermidine - Nature Chemical Biology

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The buck stops with spermidine - Nature Chemical Biology

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