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4 months ago

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Blocking methionine catabolism induces senescence and confers vulnerability to GSK3 inhibition in liver cancer - Nature Cancer

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Blocking methionine catabolism induces senescence and confers vulnerability to GSK3 inhibition in liver cancer - Nature Cancer

Availability of the essential amino acid methionine affects cellular metabolism and growth, and dietary methionine restriction has been implicated as a cancer therapeutic strategy. Nevertheless, how liver cancer cells respond to methionine deprivation and underlying mechanisms remain unclear. Here we

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Blocking methionine catabolism induces senescence and confers vulnerability to GSK3 inhibition in liver cancer - Nature Cancer

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Blocking methionine catabolism induces senescence and confers vulnerability to GSK3 inhibition in liver cancer - Nature Cancer

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