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BilR is a gut microbial enzyme that reduces bilirubin to urobilinogen - Nature Microbiology

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BilR is a gut microbial enzyme that reduces bilirubin to urobilinogen - Nature Microbiology

Metabolism of haem by-products such as bilirubin by humans and their gut microbiota is essential to human health, as excess serum bilirubin can cause jaundice and even neurological damage. The bacterial enzymes that reduce bilirubin to urobilinogen, a key step in this pathway, have remained unidentified. Here we used biochemical analyses and comparative genomics to identify BilR as a gut-microbiota-derived bilirubin reductase that reduces bilirubin to urobilinogen.

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BilR is a gut microbial enzyme that reduces bilirubin to urobilinogen - Nature Microbiology

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BilR is a gut microbial enzyme that reduces bilirubin to urobilinogen - Nature Microbiology

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