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O-GlcNAcylation mediates H2O2-induced apoptosis through regulation of STAT3 and FOXO1 - Acta Pharmacologica Sinica

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O-GlcNAcylation mediates H2O2-induced apoptosis through regulation of STAT3 and FOXO1 - Acta Pharmacologica Sinica

The O-linked-β-N-acetylglucosamine (O-GlcNAc) glycosylation (O-GlcNAcylation) is a critical post-translational modification that couples the external stimuli to intracellular signal transduction networks. However, the critical protein targets of O-GlcNAcylation in oxidative stress-induced apoptosis remain to be elucidated.

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O-GlcNAcylation mediates H2O2-induced apoptosis through regulation of STAT3 and FOXO1 - Acta Pharmacologica Sinica

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O-GlcNAcylation mediates H2O2-induced apoptosis through regulation of STAT3 and FOXO1 - Acta Pharmacologica Sinica

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