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GEMS enables mRNA m6A methylation sensing in living cells and m6A-coupled protein delivery - Nature Biotechnology

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GEMS enables mRNA m6A methylation sensing in living cells and m6A-coupled protein delivery - Nature Biotechnology

Thousands of cellular mRNAs contain the methyl modification m6A, which plays critical roles in mRNA processing and gene expression. We developed GEMS, a genetically encoded m6A sensor that provides a simple readout for m6A methylation in living cells and offers a platform for achieving m6A-coupled effector protein expression.

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GEMS enables mRNA m6A methylation sensing in living cells and m6A-coupled protein delivery - Nature Biotechnology

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GEMS enables mRNA m6A methylation sensing in living cells and m6A-coupled protein delivery - Nature Biotechnology

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