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EPAC1 boosts thermogenic adipocyte formation - Nature Cell Biology

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EPAC1 boosts thermogenic adipocyte formation - Nature Cell Biology

β-adrenergic signalling induces thermogenesis in mature brown adipocytes through a well-known cAMP–protein kinase A (PKA) pathway and also promotes the growth and differentiation of new thermogenic adipocytes. A study now demonstrates that β-adrenergic agonists drive this pathway through a PKA-independent mechanism involving cAMP–EPAC1.

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EPAC1 boosts thermogenic adipocyte formation - Nature Cell Biology

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EPAC1 boosts thermogenic adipocyte formation - Nature Cell Biology

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