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A chaperone-like function of FUS ensures TAZ condensate dynamics and transcriptional activation - Nature Cell Biology

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A chaperone-like function of FUS ensures TAZ condensate dynamics and transcriptional activation - Nature Cell Biology

The Hippo pathway has important roles in organ development, tissue homeostasis and tumour growth. Its downstream effector TAZ is a transcriptional coactivator that promotes target gene expression through the formation of biomolecular condensates. However, the mechanisms that regulate the biophysical properties of TAZ condensates to enable Hippo signalling are not well understood.

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A chaperone-like function of FUS ensures TAZ condensate dynamics and transcriptional activation - Nature Cell Biology

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A chaperone-like function of FUS ensures TAZ condensate dynamics and transcriptional activation - Nature Cell Biology

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