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A pairwise cytokine code explains the organism-wide response to sepsis - Nature Immunology

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A pairwise cytokine code explains the organism-wide response to sepsis - Nature Immunology

Sepsis is a systemic response to infection with life-threatening consequences. Our understanding of the molecular and cellular impact of sepsis across organs remains rudimentary. Here, we characterize the pathogenesis of sepsis by measuring dynamic changes in gene expression across organs. To pinpoint molecules controlling organ states in sepsis, we compare the effects of sepsis on organ gene expression to those of 6 singles and 15 pairs of recombinant cytokines. Strikingly, we

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A pairwise cytokine code explains the organism-wide response to sepsis - Nature Immunology

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A pairwise cytokine code explains the organism-wide response to sepsis - Nature Immunology

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