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Multimodal profiling reveals site-specific adaptation and tissue residency hallmarks of γδ T cells across organs in mice - Nature Immunology

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Multimodal profiling reveals site-specific adaptation and tissue residency hallmarks of γδ T cells across organs in mice - Nature Immunology

γδ T cells perform heterogeneous functions in homeostasis and disease across tissues. However, it is unclear whether these roles correspond to distinct γδ subsets or to a homogeneous population of cells exerting context-dependent functions. Here, by cross-organ multimodal single-cell profiling, we reveal that various mouse tissues harbor unique site-adapted γδ subsets.

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Multimodal profiling reveals site-specific adaptation and tissue residency hallmarks of γδ T cells across organs in mice - Nature Immunology

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Multimodal profiling reveals site-specific adaptation and tissue residency hallmarks of γδ T cells across organs in mice - Nature Immunology

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