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Pathophysiology of gastro-oesophageal reflux disease: implications for diagnosis and management - Nature Reviews Gastroenterology & Hepatology
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Gastro-oesophageal reflux disease (GERD) is a common gastrointestinal disorder in which retrograde flow of gastric content into the oesophagus causes uncomfortable symptoms and/or complications. It has a multifactorial and partially understood pathophysiology. GERD starts in the stomach, where the refluxate material is produced.
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