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An oncolytic circular RNA therapy - Nature Cancer

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An oncolytic circular RNA therapy - Nature Cancer

In vitro-transcribed RNA is a promising emerging class of therapeutic, but the poor specificity of cargo RNAs so far has limited their application in cancer immunotherapy. A new study reports the delivery of a synthetic circular RNA with inline cis-acting translational elements — encoding an engineered, mitochondrion-specific oncolytic protein — that shows both therapeutic and prophylactic potential against adenocarcinoma.

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An oncolytic circular RNA therapy - Nature Cancer

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An oncolytic circular RNA therapy - Nature Cancer

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