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Bacteroides fragilis ubiquitin homologue drives intraspecies bacterial competition in the gut microbiome - Nature Microbiology

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Bacteroides fragilis ubiquitin homologue drives intraspecies bacterial competition in the gut microbiome - Nature Microbiology

Interbacterial antagonism and associated defensive strategies are both essential during bacterial competition. The human gut symbiont Bacteroides fragilis secretes a ubiquitin homologue (BfUbb) that is toxic to a subset of B. fragilis strains in vitro. In the present study, we demonstrate that BfUbb lyses certain B. fragilis strains by non-covalently binding and inactivating an essential peptidyl-prolyl isomerase (PPIase).

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Bacteroides fragilis ubiquitin homologue drives intraspecies bacterial competition in the gut microbiome - Nature Microbiology

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Bacteroides fragilis ubiquitin homologue drives intraspecies bacterial competition in the gut microbiome - Nature Microbiology

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