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Interplay between hippocampal TACR3 and systemic testosterone in regulating anxiety-associated synaptic plasticity - Molecular Psychiatry
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Tachykinin receptor 3 (TACR3) is a member of the tachykinin receptor family and falls within the rhodopsin subfamily. As a G protein-coupled receptor, it responds to neurokinin B (NKB), its high-affinity ligand. Dysfunctional TACR3 has been associated with pubertal failure and anxiety, yet the mechanisms underlying this remain unclear.
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