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Development of cyclic peptides that can be administered orally to inhibit disease targets - Nature Chemical Biology

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Development of cyclic peptides that can be administered orally to inhibit disease targets - Nature Chemical Biology

Cyclic peptides can bind challenging disease targets, but their oral application is hindered by digestion and absorption issues. We developed a versatile method for the synthesis and functional screening of vast numbers of synthetic cyclic peptides and identified peptides with high inhibitory activity, stability and oral bioavailability in rats.

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Development of cyclic peptides that can be administered orally to inhibit disease targets - Nature Chemical Biology

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Development of cyclic peptides that can be administered orally to inhibit disease targets - Nature Chemical Biology

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