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TAAR1 agonist ulotaront modulates striatal and hippocampal glutamate function in a state-dependent manner - Neuropsychopharmacology

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TAAR1 agonist ulotaront modulates striatal and hippocampal glutamate function in a state-dependent manner - Neuropsychopharmacology

Aberrant dopaminergic and glutamatergic function, particularly within the striatum and hippocampus, has repeatedly been associated with the pathophysiology of schizophrenia. Supported by preclinical and recent clinical data, trace amine-associated receptor 1 (TAAR1) agonism has emerged as a potential new treatment approach for schizophrenia.

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TAAR1 agonist ulotaront modulates striatal and hippocampal glutamate function in a state-dependent manner - Neuropsychopharmacology

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TAAR1 agonist ulotaront modulates striatal and hippocampal glutamate function in a state-dependent manner - Neuropsychopharmacology

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