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Engineering cyanine cyclizations for new fluorogenic probes - Nature Chemistry

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Engineering cyanine cyclizations for new fluorogenic probes - Nature Chemistry

As the need for specific fluorescent probes that enable high sensitivity and super-resolution imaging experiments continues to grow, it is imperative to develop new, well-characterized methods to modulate the emission of fluorophores. Now, a general platform affords visible-to-NIR fluorogenic fluorophores by engineering a simple cyclization event into cyanine dyes.

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Engineering cyanine cyclizations for new fluorogenic probes - Nature Chemistry

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Engineering cyanine cyclizations for new fluorogenic probes - Nature Chemistry

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