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Autoantibodies against type I IFNs in humans with alternative NF-κB pathway deficiency - Nature

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Autoantibodies against type I IFNs in humans with alternative NF-κB pathway deficiency - Nature

Patients with autoimmune polyendocrinopathy syndrome type 1 (APS-1) caused by autosomal recessive AIRE deficiency produce autoantibodies that neutralize type I interferons (IFNs)1,2, conferring a predisposition to life-threatening COVID-19 pneumonia3.

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Autoantibodies against type I IFNs in humans with alternative NF-κB pathway deficiency - Nature

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Autoantibodies against type I IFNs in humans with alternative NF-κB pathway deficiency - Nature

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