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Accurate prediction of protein–nucleic acid complexes using RoseTTAFoldNA - Nature Methods

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Accurate prediction of protein–nucleic acid complexes using RoseTTAFoldNA - Nature Methods

Protein–RNA and protein–DNA complexes play critical roles in biology. Despite considerable recent advances in protein structure prediction, the prediction of the structures of protein–nucleic acid complexes without homology to known complexes is a largely unsolved problem. Here we extend the RoseTTAFold machine learning protein-structure-prediction approach to additionally predict nucleic acid and protein–nucleic acid complexes.

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Accurate prediction of protein–nucleic acid complexes using RoseTTAFoldNA - Nature Methods

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Accurate prediction of protein–nucleic acid complexes using RoseTTAFoldNA - Nature Methods

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