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5 months ago

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Viral and host mediators of non-suppressible HIV-1 viremia - Nature Medicine

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Viral and host mediators of non-suppressible HIV-1 viremia - Nature Medicine

Non-suppressible HIV-1 viremia (NSV) is defined as persistent low-level viremia on antiretroviral therapy (ART) without evidence of ART non-adherence or significant drug resistance. Unraveling the mechanisms behind NSV would broaden our understanding of HIV-1 persistence. Here we analyzed plasma virus sequences in eight ART-treated individuals with NSV (88% male) and show that they are composed of large clones without evidence of viral evolution over time in those with longitudinal samples.

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Viral and host mediators of non-suppressible HIV-1 viremia - Nature Medicine

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Viral and host mediators of non-suppressible HIV-1 viremia - Nature Medicine

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