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6 months ago

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Mechanism of sperm mtDNA elimination - Nature Reviews Molecular Cell Biology

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Mechanism of sperm mtDNA elimination - Nature Reviews Molecular Cell Biology

Phosphorylation of the mitochondrial DNA (mtDNA) maintenance factor TFAM during spermatogenesis prevents its import into mitochondria, resulting in elimination of paternal mtDNA and leading to maternal inheritance.

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Mechanism of sperm mtDNA elimination - Nature Reviews Molecular Cell Biology

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Mechanism of sperm mtDNA elimination - Nature Reviews Molecular Cell Biology

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