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Phase-separation behaviour of RNAs - Nature Chemistry

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Phase-separation behaviour of RNAs - Nature Chemistry

Ribonucleoprotein granules are ubiquitous in living organisms with the protein and RNA components having distinct roles. In the absence of proteins, RNAs are shown to undergo phase separation upon heating. This transition is driven by desolvation entropy and ion-mediated crosslinking and is tuned by the chemical specificity of the RNA nucleobases.

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Phase-separation behaviour of RNAs - Nature Chemistry

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