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Non-synaptic function of the autism spectrum disorder-associated gene SYNGAP1 in cortical neurogenesis - Nature Neuroscience

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Non-synaptic function of the autism spectrum disorder-associated gene SYNGAP1 in cortical neurogenesis - Nature Neuroscience

Genes involved in synaptic function are enriched among those with autism spectrum disorder (ASD)-associated rare genetic variants. Dysregulated cortical neurogenesis has been implicated as a convergent mechanism in ASD pathophysiology, yet it remains unknown how 'synaptic' ASD risk genes contribute to these phenotypes, which arise before synaptogenesis.

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Non-synaptic function of the autism spectrum disorder-associated gene SYNGAP1 in cortical neurogenesis - Nature Neuroscience

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Non-synaptic function of the autism spectrum disorder-associated gene SYNGAP1 in cortical neurogenesis - Nature Neuroscience

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