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Structural basis for the activity regulation of Salt Overly Sensitive 1 in Arabidopsis salt tolerance - Nature Plants

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Structural basis for the activity regulation of Salt Overly Sensitive 1 in Arabidopsis salt tolerance - Nature Plants

The plasma membrane Na+/H+ exchanger Salt Overly Sensitive 1 (SOS1) is crucial for plant salt tolerance. Unlike typical sodium/proton exchangers, SOS1 contains a large cytoplasmic domain (CPD) that regulates Na+/H+ exchange activity. However, the underlying modulation mechanism remains unclear. Here we report the structures of SOS1 from Arabidopsis thaliana in two conformations, primarily differing in CPD flexibility.

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Structural basis for the activity regulation of Salt Overly Sensitive 1 in Arabidopsis salt tolerance - Nature Plants

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Structural basis for the activity regulation of Salt Overly Sensitive 1 in Arabidopsis salt tolerance - Nature Plants

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