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Accelerated epigenetic aging and decreased natural killer cells based on DNA methylation in patients with untreated major depressive disorder - npj Aging

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Accelerated epigenetic aging and decreased natural killer cells based on DNA methylation in patients with untreated major depressive disorder - npj Aging

Major depressive disorder (MDD) is known to cause significant disability. Genome-wide DNA methylation (DNAm) profiles can be used to estimate biological aging and as epigenetic clocks. However, information on epigenetic clocks reported in MDD patients is inconsistent. Since antidepressants are likely confounders, we evaluated biological aging using various DNAm-based predictors in patients with MDD who had never received depression medication.

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Accelerated epigenetic aging and decreased natural killer cells based on DNA methylation in patients with untreated major depressive disorder - npj Aging

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Accelerated epigenetic aging and decreased natural killer cells based on DNA methylation in patients with untreated major depressive disorder - npj Aging

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for Humanity's Progress