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6 months ago

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Efficacy and safety in mice of repeated, lifelong administration of an ANGPTL3 vaccine - npj Vaccines

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Efficacy and safety in mice of repeated, lifelong administration of an ANGPTL3 vaccine - npj Vaccines

Previously, we reported that an ANGPTL3 vaccine is a hopeful therapeutic option against dyslipidemia. In our current study, we assess durability and booster effects of that vaccine over a period representing a mouse's lifespan. The vaccine remained effective for over one year, and booster vaccination maintained suppression of circulating triglyceride levels thereafter without major adverse effects on lungs, kidneys, or liver, suggesting vaccine efficacy and safety.

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Efficacy and safety in mice of repeated, lifelong administration of an ANGPTL3 vaccine - npj Vaccines

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Efficacy and safety in mice of repeated, lifelong administration of an ANGPTL3 vaccine - npj Vaccines

Rate This Post

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Unlocking the Power of Knowledge
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