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6 months ago

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Mouse genome rewriting and tailoring of three important disease loci - Nature

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Mouse genome rewriting and tailoring of three important disease loci - Nature

Genetically engineered mouse models (GEMMs) help us to understand human pathologies and develop new therapies, yet faithfully recapitulating human diseases in mice is challenging. Advances in genomics have highlighted the importance of non-coding regulatory genome sequences, which control spatiotemporal gene expression patterns and splicing in many human diseases1,2.

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Mouse genome rewriting and tailoring of three important disease loci - Nature

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Mouse genome rewriting and tailoring of three important disease loci - Nature

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