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Spermidine promotes fertility in aged female mice - Nature Aging

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Spermidine promotes fertility in aged female mice - Nature Aging

Female fecundity decreases one to two decades before the menopausal transition. A study by Zhang et al. now identifies aging-related decline of the polyamine spermidine as a crucial bottleneck for oocyte quality. Supplementation with spermidine rejuvenates oocytes in vitro and in vivo, and leads to improved fertility of middle-aged female mice.

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Spermidine promotes fertility in aged female mice - Nature Aging

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Spermidine promotes fertility in aged female mice - Nature Aging

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