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Hijacking host ribosomes via tRNA mimicry - Nature Cell Biology

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Hijacking host ribosomes via tRNA mimicry - Nature Cell Biology

The bacterial pathogen Legionella pneumophila uses effectors — toxins — to facilitate pathogenesis within host cells. A recent study identifies dual mechanisms of the effector SidI as an inhibitor of translation elongation. The N-terminal domain mimics tRNA, whereas the C-terminal domain glycosylates the ribosome.

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Hijacking host ribosomes via tRNA mimicry - Nature Cell Biology

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Hijacking host ribosomes via tRNA mimicry - Nature Cell Biology

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