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Accurate computational design of three-dimensional protein crystals - Nature Materials

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Accurate computational design of three-dimensional protein crystals - Nature Materials

Protein crystallization plays a central role in structural biology. Despite this, the process of crystallization remains poorly understood and highly empirical, with crystal contacts, lattice packing arrangements and space group preferences being largely unpredictable. Programming protein crystallization through precisely engineered side-chain–side-chain interactions across protein–protein interfaces is an outstanding challenge.

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Accurate computational design of three-dimensional protein crystals - Nature Materials

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Accurate computational design of three-dimensional protein crystals - Nature Materials

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