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Adaptive preservation of orphan ribosomal proteins in chaperone-dispersed condensates - Nature Cell Biology

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Adaptive preservation of orphan ribosomal proteins in chaperone-dispersed condensates - Nature Cell Biology

Ribosome biogenesis is among the most resource-intensive cellular processes, with ribosomal proteins accounting for up to half of all newly synthesized proteins in eukaryotic cells. During stress, cells shut down ribosome biogenesis in part by halting rRNA synthesis, potentially leading to massive accumulation of aggregation-prone 'orphan' ribosomal proteins (oRPs).

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Adaptive preservation of orphan ribosomal proteins in chaperone-dispersed condensates - Nature Cell Biology

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Adaptive preservation of orphan ribosomal proteins in chaperone-dispersed condensates - Nature Cell Biology

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