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Dietary and commensal yeasts drive aberrant T cell responses in Crohn's disease - Nature Medicine

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Dietary and commensal yeasts drive aberrant T cell responses in Crohn's disease - Nature Medicine

Aberrant immune responses to the intestinal microbiome have emerged as major contributors to chronic intestinal inflammation, but the microbial species involved in inflammatory bowel diseases remain unknown. Our study identified dietary and commensal yeasts of the gut that drive the expansion of some cross-reactive CD4+ type 1 helper T cells with cytotoxic effector functions, which potentially contributes to immunopathology in patients with Crohn's disease.

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Dietary and commensal yeasts drive aberrant T cell responses in Crohn's disease - Nature Medicine

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Dietary and commensal yeasts drive aberrant T cell responses in Crohn's disease - Nature Medicine

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