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Slack K+ channels limit kainic acid-induced seizure severity in mice by modulating neuronal excitability and firing - Communications Biology

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Slack K+ channels limit kainic acid-induced seizure severity in mice by modulating neuronal excitability and firing - Communications Biology

Mutations of the Na+-activated K+ channel Slack (KCNT1) are associated with terrible epilepsy syndromes that already begin in infancy. Here we report increased severity of acute kainic acid-induced seizures in adult and juvenile Slack knockout mice (Slack−/−) in vivo. Fittingly, we

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Slack K+ channels limit kainic acid-induced seizure severity in mice by modulating neuronal excitability and firing - Communications Biology

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Slack K+ channels limit kainic acid-induced seizure severity in mice by modulating neuronal excitability and firing - Communications Biology

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Unlocking the Power of Knowledge
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Unlocking the Power of Knowledge
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