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Genome-wide association study on pharmacological outcomes of musculoskeletal pain in UK Biobank - The Pharmacogenomics Journal

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Genome-wide association study on pharmacological outcomes of musculoskeletal pain in UK Biobank - The Pharmacogenomics Journal

The pharmacological management of musculoskeletal pain starts with NSAIDs, followed by weak or strong opioids until the pain is under control. However, the treatment outcome is usually unsatisfying due to inter-individual differences. To investigate the genetic component of treatment outcome differences, we performed a genome-wide association study (GWAS) in ~23,000 participants with musculoskeletal pain from the UK Biobank. NSAID vs.

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Genome-wide association study on pharmacological outcomes of musculoskeletal pain in UK Biobank - The Pharmacogenomics Journal

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Genome-wide association study on pharmacological outcomes of musculoskeletal pain in UK Biobank - The Pharmacogenomics Journal

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