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Molecular pathology of neurodegenerative diseases by cryo-EM of amyloids - Nature

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Molecular pathology of neurodegenerative diseases by cryo-EM of amyloids - Nature

Abnormal assembly of tau, α-synuclein, TDP-43 and amyloid-β proteins into amyloid filaments defines most human neurodegenerative diseases. Genetics provides a direct link between filament formation and the causes of disease. Developments in cryo-electron microscopy (cryo-EM) have made it possible to determine the atomic structures of amyloids from postmortem human brains.

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Molecular pathology of neurodegenerative diseases by cryo-EM of amyloids - Nature

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Molecular pathology of neurodegenerative diseases by cryo-EM of amyloids - Nature

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