@curator

7 months ago

Article

APOE4 impairs the microglial response in Alzheimer's disease by inducing TGFβ-mediated checkpoints - Nature Immunology

Rating: 0.0

Likes: 1

Library: 1

APOE4 impairs the microglial response in Alzheimer's disease by inducing TGFβ-mediated checkpoints - Nature Immunology

The APOE4 allele is the strongest genetic risk factor for late-onset Alzheimer's disease (AD). The contribution of microglial APOE4 to AD pathogenesis is unknown, although APOE has the most enriched gene expression in neurodegenerative microglia (MGnD). Here, we show in mice and humans a negative role of microglial APOE4 in the induction of the MGnD response to neurodegeneration.

Rate This Post

Rate The Educational Value

Rate The Ease of Understanding and Presentation

Interesting or Boring? Rate the Entertainment Value

Related Topics

productivity business technology software app computer microglial mediated checkpoints

Learning is Fun!

Close

Learning is Fun!

Close

Learning is Fun!

Close

Learning is Fun!

Close

Learning is Fun!

Close

Learning is Fun!

Close

Add articles, eBooks or videos to your Library.
You can revisit, watch or read your favorite items later

Learning is Fun!

Close

Unlocking the Power of Knowledge
for Humanity's Progress

By harnessing the power of Artificial Intelligence, Boostlane is changing the way we engage with information, connect with experts, and foster personal growth.

Explore Topics,
Discover Ideas,
Share knowledge,
Learn from Experts

Boostlane is a media platform that aims to revolutionize how we research, discover, and learn about our favorite topics

Boostlane relies on the power of Artificial Intelligence and a Community of Researchers to curate and deliver reliable, insightful, and purposeful knowledge

Support a platform focused on research and useful knowledge.
Create personalized feeds.
Follow your favorite topics and learn something new every day.
Learn with the assistance of people and Artificial Intelligence Systems.
Use innovative features designed to organize information and foster personal growth.
Collect your favorite media in your private Library.

Learning is Fun!

Close

Learning is Fun!

Close

Learning is Fun!

Close

Unlocking the Power of Knowledge
for Humanity's Progress

By harnessing the power of Artificial Intelligence, Boostlane is changing the way we engage with information, connect with experts, and foster personal growth.

Explore Topics,
Discover Ideas,
Share knowledge,
Learn from Experts

Boostlane is a media platform that aims to revolutionize how we research, discover, and learn about our favorite topics

Boostlane relies on the power of Artificial Intelligence and a Community of Researchers to curate and deliver reliable, insightful, and purposeful knowledge

Support a platform focused on research and useful knowledge.
Create personalized feeds.
Follow your favorite topics and learn something new every day.
Learn with the assistance of people and Artificial Intelligence Systems.
Use innovative features designed to organize information and foster personal growth.
Collect your favorite media in your private Library.

APOE4 impairs the microglial response in Alzheimer's disease by inducing TGFβ-mediated checkpoints - Nature Immunology

Rate This Post

Related Topics

Comments

Media:

My Account:

Boostlane:

Select a Category

Topics Trending Today

Recommended Media

Boostlane Reward System

Unlocking the Power of Knowledge
for Humanity's Progress

Quick Links

Select a Locale

Unlocking the Power of Knowledge
for Humanity's Progress

APOE4 impairs the microglial response in Alzheimer's disease by inducing TGFβ-mediated checkpoints - Nature Immunology

Rate This Post

Related Topics

Comments

Media:

My Account:

Boostlane:

Select a Category

Topics Trending Today

Recommended Media

Boostlane Reward System

Unlocking the Power of Knowledge for Humanity's Progress

Quick Links

Select a Locale

Unlocking the Power of Knowledge for Humanity's Progress

Unlocking the Power of Knowledge
for Humanity's Progress

Unlocking the Power of Knowledge
for Humanity's Progress