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Skani enables accurate and efficient genome comparison for modern metagenomic datasets - Nature Methods

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Skani enables accurate and efficient genome comparison for modern metagenomic datasets - Nature Methods

Modern high-throughput metagenomics is producing hundreds of thousands of metagenome-assembled genomes (MAGs), which is overwhelming traditional sequence-similarity search methods. We present a computational method, skani, that efficiently compares MAGs on a terabyte scale while being robust to the inherent noise in MAGs, enabling larger and more accurate analyses.

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Skani enables accurate and efficient genome comparison for modern metagenomic datasets - Nature Methods

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Skani enables accurate and efficient genome comparison for modern metagenomic datasets - Nature Methods

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