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Dissecting key regulators of transcriptome kinetics through scalable single-cell RNA profiling of pooled CRISPR screens - Nature Biotechnology

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Dissecting key regulators of transcriptome kinetics through scalable single-cell RNA profiling of pooled CRISPR screens - Nature Biotechnology

We present a combinatorial indexing method, PerturbSci-Kinetics, for capturing whole transcriptomes, nascent transcriptomes and single guide RNA (sgRNA) identities across hundreds of genetic perturbations at the single-cell level.

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Dissecting key regulators of transcriptome kinetics through scalable single-cell RNA profiling of pooled CRISPR screens - Nature Biotechnology

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Dissecting key regulators of transcriptome kinetics through scalable single-cell RNA profiling of pooled CRISPR screens - Nature Biotechnology

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